Writing a coherent and cohesive comparison-contrast essay has always proved challenging for university students, affecting their academic and professional achievement. Therefore, this research investigated how teachers and learners could adopt a writing guide which focused on the techniques of coherence as well as grammatical and lexical cohesion to enhance the students’ comparison-contrast essays. Applying the quasi-experimental research design, a population of eighty-eight students from the intensive English course INTE 103 at Beirut Arab University during fall 2024 was divided into two groups: experimental and control. Both groups took a pre-/post-test. The experimental group students were subjected to a treatment for ten weeks during which they wrote four essays using the writing guide. Data from the essays were collected and analyzed. Findings revealed that consciously employing the skills of coherence and cohesion contributed to enhancing the participants’ comparison-contrast essay writing. Based on the results, the experiment as a whole proved that, through the use of the comparison-contrast coherence-cohesion writing guide, participating students’ comparison-contrast essay writing skills showed remarkable improvement at the coherence as well as grammatical and lexical cohesion levels. Finally, it is recommended that teachers and students use the comparison-contrast writing guide through various in-class activities to help students develop a well-written comparison-contrast essay with strong coherence and cohesion.