Effect of psychosocial aspects on medication adherence in patients with heart failure amid socioeconomic challenges
Abstract
ABSTRACT
Objective To evaluate stress, depression and quality
of life among community-dwelling patients with heart
failure (HF) and evaluate their effect on perceived
medication adherence in a socioeconomically
challenged setting.
Design A cross-sectional design with self-administered
questionnaire with data collected between October 2021
and September 2022.
Methods Patients with confirmed diagnosis of HF
were sought for data collection in the community
and cardiology clinics through an electronic platform.
Confirmation of cases was done through the ejection
fraction, medication list and frequent symptoms of
the patients. The Patient Health Questionnaire-9, the
COVID-19 Stress Scale, the Minnesota Living with HF
Questionnaire and the Lebanese Medication Adherence
Scale were used to evaluate depression, stress,
quality of life and medication adherence, respectively.
Univariate analysis was done to present the descriptive
statistics, whereas bivariate and multivariate analyses
were done to evaluate the relationship between the
variables.
Results A total of 237 participants were included in the
final analysis. The mean age was 61.3±17.36 years, and
the majority (57.8%) were male participants. Only 44.7%
were on ACE inhibitors/angiotensin receptor blockers and
54.9% on beta-blockers. The mean scores for stress,
depression, quality of life and medication adherence were
75.86 (SD=24.5), 14.03 (SD=5.7), 55.73 (SD=23.05) and
6.79 (SD=6.93), respectively, indicating high stress levels,
depression, poor quality of life and medication adherence.
Those with a history of hypertension and depression were
significantly more adherent to their medications than
those who were not. Multivariate analysis showed that
anxiety, medical follow-up, quality of life and functionality
class were predictors of medication adherence.
Conclusion The study showed the population with
HF in Lebanon to have psychological health problems
with these variables acting as predictors for medication
adherence. Sociodemographic characteristics also
played a role on the outcome, which can be targeted
when planning interventions to improve outcomes.
Future studies should compare prescribed medication
with consumed medication through longitudinal
approaches and medical refilling techniques when
possible.
Journal/Conference Information
Nursing Open,DOI: 10.1136/openhrt-2023-002550, ISSN: 2054-1058, Volume: 11, Issue: 1, Pages Range: 1-10,