This 7 weeks module allows the students to apply knowledge learnt in previous semesters to the diagnosis, and understanding of common illnesses, conditions and disorders, their pathophysiology and pharmacology. It enables students to use the basic sciences knowledge in a conceptual context to construct algorithmic maps for common clinical problems in a critical thinking and clinical-wise approach. The module also introduces students to research methodologies including the biostatistics, types of variables, data collection and data presentation, and medical informatics. It raises their acquaintance with the scientific design and limitations of the various study types. Students will learn how to apply key principles in evidence based medicine. Student’s awareness of legal and ethical issues, professional rights and responsibilities, patient advocacy, and working in multi-disciplinary teams will also be met. Prerequisites: CARD 205, GITN 206,RENR 208, RESP 207.