There was a surge of change during the Coronavirus period—even in the way we thought about architecture principles to improve sustainability. This period of quarantine gave scientists time to reconsider the main principles behind theories of sustainable housing because many new factors had emerged, such as the health and wellbeing of occupants, the science of providing a clean indoor environment without the contamination of coronavirus, etc. People eventually adjusted to the prevailing situation despite a lot of discrepancies initially, allowing them to continue functioning. A temporary change is one type of change, while a permanent change is another. After the outbreak of COVID, residential architecture has also seen many changes in priorities, just like any other industry. Changes in lifestyles and habits have influenced home designs. A sustainable housing environment needs to be addressed in the design and construction sectors. With this disease affecting our design and construction methods, as well as standards and regulations, how should we adjust and review them? In what ways can new technologies in construction and design make a difference? Architects face a huge challenge now, compared to before the Coronavirus period, with new houses since there is no guarantee that the indoor spaces will be free from Coronavirus contamination. Creating a safe, clean, and sustainable dwelling in the post-pandemic age is the goal of this chapter. It explains the principles that can assist in creating a clean environment in the house. One of the most significant contributions of this chapter is the formulation of new theories and principles for sustainable housing in the post-pandemic era. The development of guidelines or a framework for architects intent on designing sustainable housing concepts worldwide is also a contribution.