Mohammed M. Mehanna studied pharmaceutical sciences at the Faculty of Pharmacy, Alexandria University. Mohammed received his B.Sc. and M.Sc. degree (with the highest honours) in Pharmaceutical Sciences from Alexandria University in 2001 and 2008, respectively. In 2010, Mohammed received his Doctor of Philosophy in Pharmaceutical sciences from the same university . Mohammed spent the academic year 2013/2014 as Visiting Assistant Professor at the University of Mutah, Hashemite Kingdom of Jordan. In 2012, Mohammed joined Department of Pharmaceutical Technology, Faculty of Pharmacy at Beirut Arab University as an Assistant Professor. In 2016, Mohammed was promoted to Associate Professor. His research interests cover the field of nanopharmacuticals and modern drug delivery systems such as lipid and polymer-based nanostructures for a wide variety of pharmaceutical applications. He has published several research articles in the field of nanocarriers as vehicle for drug delivery.
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My research interest currently focuses on two main areas: at the macro-pharmaceutical level, I’m interesting in developing non-invasive drug delivery systems with a particular emphasis on tailoring carriers through different routes of administration. Fundamental pharmaceutical concepts in drug solubilization and controlled-release drug delivery are of interest. In addition to, the elaboration and appraisal procedures and techniques of micro-sized pharmaceutical carriers. Mathematical optimization and assessment of delivery systems covers various routes of administration viz. oral, transdermal, pulmonary and ocular is considered an area of my speciality. At the nanotechnology level, my core of research is the application of nanotechnology in the field of drug delivery with special interest in anticancer and anti-bacterial drugs and targeting. More precisely, these investigations of polymer-, lipid- and peptide-based nano-carriers allow us to explore their in vivo performance on molecular and animal models.
1. Mohammed M. Mehanna, Souraya Domiati, Hanan Ragab, Hania Nakkash Chmaisse, Ahmed El Mallah. “Antinociceptive Effect of Tadalafil in Various Pain Models: Involvement of Opioid Receptors and Nitric Oxide cyclic GMP Pathways” Journal of Toxicology and Applied Pharmacology, 2018; 352: 170-175
2. Souraya Domiati, Mohammed M. Mehanna, Hanan Ragab, Hania Nakkash Chmaisse, Ahmed El Mallah. “Investigation of chronic efficacy and safety profile of two potential anti-inflammatory bipyrazole-based compounds in experimental animals” Journal of Inflammation Research, 2018; 11:143-153
3. Mohammed M. Mehanna, Nourane Abdelkader, Magda W. Samaha. “Liposomes as a potential carrier for ketorolac ophthalmic delivery: formulation and stability issues” Brazilian Journal of Pharmaceutical Sciences, 2017; 53(2):e16127
4. Mohammed M. Mehanna. “Design and physicochemical characterization of isinopril–loaded nanocapsules for paediatric use", International Journal of Pharmacy and Technology, 2016; 9(1): 28149-28162
5. Salma M. Mohyeldin, Mohammed M. Mehanna, Nazik A. Elgindy. “Superiority of liquid crystalline cubic nanocarriers as hormonal transdermal vehicle: comparative human skin permeation-supported evidence”. Expert Opinion on Drug Delivery, 2016;13(8): 1049-1064
6. Salma M. Mohyeldin, Mohammed M. Mehanna, Nazik A. Elgindy. “The relevancy of controlled nanocrystallization on rifampicin characteristics and cytotoxicity”. International Journal of Nanomedicine, 2016;11: 2209—2222
7. Nazik A. Elgindy, Mohammed M. Mehanna, Salma M. Mohyeldin. “Self-assembled nano-architecture liquid crystalline particles as a promising carrier for progesterone transdermal delivery”. International Journal of Pharmaceutics, 2016; 501: 167–179
8. Ahmed Allam, Mohammed M. Mehanna. Formulation, physicochemical characterization and in-vivo evaluation of ion-sensitive metformin loaded-biopolymeric beads. Drug Development and Industrial Pharmacy. 2016; 42(3): 497–505
a. Journal of Novel Drug Delivery Technology
b. Insights in Tuberculosis
c. Journal of Bioavailability and Bioequivalence
d. International Journal of Pharmacy and Biotechnology
International Journal of Pharmaceutics.
International Journal of Nanomedicine.
Journal of Pharmaceutical Science.
Journal of Molecular Pharmaceutics.
Drug Design, Development and Therapy
Drug Development and Industrial Pharmacy.
Journal AOAC International