PHAR 273 Pharm. Org. Chem. III

PHAR 273 Pharm. Org. Chem. III

Department offering the course: Pharmaceutical Sciences
Level [Semester]: First [Spring]

Basic Information
Total Credit Hours: 3
Lecture: 2
Practical: 2
Professional Information
Course Description:
The course delivers knowledge of natural molecules such as carbohydrates, amino acids, peptides and proteins. Specialized evidences concerning polynuclear hydrocarbons, heterocyclic chemistry and their applicability in the field of medicinal drugs synthesis are deeply argued, in addition to adequate familiarity to different spectroscopic techniques.
Overall aims:
The prime objective of this course is to develop a sense of enthusiasm for Pharmaceutical Organic Chemistry and its broad applications so that the student could continue Medicinal Chemistry courses and further studies as Biochemistry, Analytical Chemistry, Phytochemistry and other pharmacy branches. In addition the course enables the student to apply acquired Organic Chemistry knowledge in industry after his graduation. It provides students with the basic knowledge in the field of mechanistic Organic Chemistry with an overall view of the basic synthetic techniques and applicability in the field of synthesis of medicinal drugs. It shows students, by means of structural and mechanistic aspects, what organic chemistry does in living systems both in biological terms and in our physical environment. In addition, the students will have widespread information in the field of natural compounds such as carbohydrates, amino acids, polypeptides and proteins with reference to the encountered stereochemistry. An important objective of the course also is to provide specialized knowledge of different aspects of Heterocyclic Chemistry and to integrate this knowledge with those of Medicinal Chemistry and other branches in order to perfectly apply them in professional Pharmaceutical Chemistry practice. It helps the students to acquire skills to suggest the proper nomenclature for heterocyclic organic compounds with special reference to drugs. Furthermore, the course would provide the students with adequate knowledge about spectroscopic techniques that enable him/her to interpret the structure of various organic compounds. The course also includes practical skills in organic chemistry thus helping the student to identify and synthesize various organic compounds.

Pre-requisite: PHAR 262

Time Table:
Lecture :    Monday 2-4 pm        
Lab :    Tuesday 12-2 pm        
Office Hours:    Thursday 10-12 am        

Assessment  Methods:

- Mid-term written examination
- Practical Examinations
- Oral examination
- Final written examination

List of References

- Textbook of Organic Medicinal and Pharmaceutical Chemistry, Wilson and Gisvold's, 11th Ed.,  Philadelphia : Lippincott Williams & Wilkins, 2004.
- Organic Chemistry ,T. W. Graham Solomons, Craig B. Fryhle, 9th Ed., N.Y.:     John Wiley & Sons, Inc., 2006.
- Organic Chemistry, T. W. Graham Solomons, Craig B. Fryhle, 8th Ed., N.Y.: John Wiley & Sons, Inc., 2004.
- March's Advanced Organic Chemistry,: Reactions, Mechanisms, And Structure, Michael B. Smith and Jerry
- March, 6th Ed., New Jersey : John Wiley and Sons, Inc., 2007.
- Organic Chemistry, John McMurry, 7th Ed., Australia : Thomson Brooks/Cole, 2008.

Further reading:

- Textbook of Organic Medicinal and Pharmaceutical Chemistry, Wilson and Gisvold's, 12th Ed., International
- Edition, Philadelphia : Lippincott Williams & Wilkins, 2011.