The course intends to elaborate fundamentals of medicinal chemistry; it starts with an introduction to physiochemical properties of drugs relative to their biological effects. The course is developed to highlight the concept of drug discovery and development throughout studying chemical and biochemical aspects of certain drug categories including those affecting neurotransmission, local anesthetics, respiratory and gastrointestinal drugs. Satisfactory awareness of the chemistry of antibiotics, antibacterial sulfonamides, quinolones, and antimycobacterial agents is also undertaken. The course helps students to acquire adequate comprehension of potential drug instabilities, interactions and side effects, supporting them meeting patient’s needs. The practical part of the course develops students’ ethical and professional responsibilities and raises their decision-making skills.
Pre-requisites: PHAR 273, PHAR 280